Acute Kidney Injury (AKI) can occur when:

• There’s a sudden, serious drop in blood flow to the kidneys. Heavy blood loss, an injury, or a bad infection called sepsis can reduce blood flow to the kidneys. Not enough fluid in the body (dehydration) also can harm the kidneys.

• There's direct damage to your kidneys from medications or injury.

•There’s a sudden blockage that prevents urine from flowing out of the kidneys.